WHO Pneumonia Evidence Review

​Pneumonia remains one of the leading causes of death in children under five, with those suffering from severe pneumonia facing the greatest risk. 

​Melbourne Children’s Global Health reviewed the global evidence for the World Health Organization (WHO) to improve the prevention, diagnosis, and treatment of pneumonia in children and adolescents—particularly in low- and middle-income countries, where the burden is highest. 

Evidence Reviews

The utility of chest x-ray and lung ultrasound in the management of infants and children presenting with severe pneumonia in low-and middle-income countries: A pragmatic scoping review - PubMed

Systematic review on the impact of the pneumococcal conjugate vaccine ten valent (PCV10) or thirteen valent (PCV13) on all-cause, radiologically confirmed and severe pneumonia hospitalisation rates and pneumonia mortality in children 0-9 years old - PubMed

Can child pneumonia in low-resource settings be treated without antibiotics? A systematic review & meta-analysis - PubMed

Continuous Positive Airway Pressure (CPAP) for severe pneumonia in low- and middle-income countries: A systematic review of contextual factors - PubMed

Which children with chest-indrawing pneumonia can be safely treated at home, and under what conditions is it safe to do so? A systematic review of evidence from low- and middle-income countries - PubMed

Review of the role of additional treatments including oseltamivir, oral steroids, macrolides, and vitamin supplementation for children with severe pneumonia in low- and middle-income countries - PubMed

Systematic review of the clinical outcomes of pneumonia with a penicillin-group resistant pneumococcus in respiratory and blood culture specimens in children in low- and middle-income countries - PubMed

Aetiology of childhood pneumonia in low- and middle-income countries in the era of vaccination: a systematic review - PubMed

Childhood pneumonia in humanitarian emergencies in low- and middle-income countries: A systematic scoping review - PubMed